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The genes studied are involved in regulation of the NFB pathway ( TLR2 , TLR4 , TLR5 , TLR9 , LY96 , CD14 , MAP3K14 , SUMO4 , NFKBIA and NFKB1 ), TNF- signaling ( TNFA , TNFRSF1A and TNFAIP3 ), cytokines regulated by NFB ( IL1B , IL1RN , IL6 , IL10 , IL17A and IFNG ) and other genes involved in regulation of inflammation ( IL4R , IL6R , IL23R , TGFB1 , PTPN22 , PPARG and NLRP3 )

They were randomly divided into 4 groups of 5 animals each

doi: 10.1016/j.cell.2022.06.003 33 LaiBWuCHWuCYLuoSFLaiJH

Critical role of FOXO3a in carcinogenesis

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